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Karolinska Institutet -SciLifeLab
Stockholm, , Sweden


 

Company Description:

Pelechano group combines experimental and computational approaches to develop and apply novel genome-wide techniques to investigate eukaryotic transcription and gene expression (Pelechano et al.Nature 2013, Chabbert et al. Mol. Syst. Biol. 2015, Pelechano et al. Cell 2015). 

We are especially interested in understanding the regulatory mechanisms leading to the appearance of divergent gene expression programs in clonal cell population (http://pelechanolab.com/). Different cells in a population can present varying responses to the same stimulus. In some cases these differences are attributable to genetic mutations, such as the appearance of drug-resistant cells in bacterial and cancer populations. However, in other cases identical (clonal) cells can also display phenotypically heterogeneous responses. This non-genetic heterogeneity has a poorly understood origin but a significant impact on biology and human health.

Our lab is located in the newly established Science for Life Laboratory (SciLifeLab, http://www.scilifelab.se/) in the Karolinska Institute campus. SciLifeLab is equiped with state-of-the-art instrumentation and core facilities, and is home to the second largest sequencing cluster in Europe. SciLifeLab Stockholm is a joint effort between Karolinska Institute, the Swedish Royal Institute of Technology (KTH) and Stockholm University, and hosts research groups with diverse backgrounds and expertise, including basic biology, drug discovery, genomics, bioengineering, and translational medicine.


Jobs by Karolinska Institutet -SciLifeLab
Results: 1 Job
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Title (show brief) Location Posted Down
Postdoctoral fellow in Genomics or Computational Biology Stockholm 11.02.2017
MTC is offering a postdoctoral stipend position in the field of Computational Biology to work in the group of Dr....
 
Title Postdoctoral fellow in Genomics or Computational Biology
Location Stockholm
Posted 11.02.2017
show brief MTC is offering a postdoctoral stipend position in the field of Computational Biology to work in the group of Dr....
 

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